New empirical Bayes methods aiming at analyzing the association of single nucleotide polymorphisms (SNPs) to some particular disease are implemented in this package. The package uses local false discovery rate (LFDR) estimates of SNPs within a sample population defined as a "reference class" and discovers if SNPs are associated with the corresponding disease. Although SNPs are used throughout this document, other biological data such as protein data and other gene data can be used. Karimnezhad, Ali and Bickel, D. R. (2016) <http://hdl.handle.net/10393/34889>.
Version: | 1.0 |
Depends: | R (≥ 2.14.2) |
Imports: | matrixStats, stats, R6 |
Suggests: | LFDR.MLE, testthat |
Published: | 2017-09-27 |
DOI: | 10.32614/CRAN.package.LFDREmpiricalBayes |
Author: | Ali Karimnezhad, Johnary Kim, Anna Akpawu, Justin Chitpin and David R Bickel |
Maintainer: | Ali Karimnezhad <ali_karimnezhad at yahoo.com> |
License: | GPL-3 |
URL: | https://davidbickel.com |
NeedsCompilation: | no |
Materials: | NEWS |
CRAN checks: | LFDREmpiricalBayes results |
Reference manual: | LFDREmpiricalBayes.pdf |
Vignettes: |
LFDREmpiricalBayes (source, R code) |
Package source: | LFDREmpiricalBayes_1.0.tar.gz |
Windows binaries: | r-devel: LFDREmpiricalBayes_1.0.zip, r-release: LFDREmpiricalBayes_1.0.zip, r-oldrel: LFDREmpiricalBayes_1.0.zip |
macOS binaries: | r-release (arm64): LFDREmpiricalBayes_1.0.tgz, r-oldrel (arm64): LFDREmpiricalBayes_1.0.tgz, r-release (x86_64): LFDREmpiricalBayes_1.0.tgz, r-oldrel (x86_64): LFDREmpiricalBayes_1.0.tgz |
Reverse suggests: | CorrectedFDR |
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